Marcel Dinger - Profile - Revision history

Marceld: /* Biography */

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‎Biography

Marceld: /* Publications */

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‎Publications

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‎Biography

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‎Publications

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‎Publications

Marceld: /* Biography */

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‎Biography

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‎Publications

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‎Biography

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‎Biography

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‎Biography

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 <table><tr><td>
-Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 172 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 74]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
+Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 172 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 75]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
 Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research]. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome. Prior to moving to Sydney, Marcel headed the Cancer Transcriptomics laboratory at the [http://www.di.uq.edu.au/ Diamantina Institute] at the [http://www.uq.edu.au/ University of Queensland]. Marcel undertook his postdoctoral studies at the [http://imb.uq.edu.au/ Institute for Molecular Bioscience] where he studied the role of long noncoding RNAs in mammalian development and disease. During his postdoc, Marcel led a number of key studies demonstrating the dynamic and specific expression of long noncoding RNAs that prompted extensive functional studies of these transcripts that were commonly assumed to be “junk”.

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 <nowiki>*</nowiki> '''Authors contributed equally'''
-#Ross SE, Holliday H, Wang E, Zeraati M, Tsoli M, Ziegler DS, '''Dinger ME''' (2026). [https://www.nature.com/articles/s41419-026-08647-8 RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.] ''Cell Death and Disease'' Published online March 26. doi: 10.1038/s41419-026-08647-8.
+#Ross SE, Holliday H, Wang E, Zeraati M, Tsoli M, Ziegler DS*, '''Dinger ME'''* (2026). [https://www.nature.com/articles/s41419-026-08647-8 RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.] ''Cell Death and Disease'' Published online March 26. doi: 10.1038/s41419-026-08647-8.
 #Adey BN, Maddock DJ, Hermann-Le Denmat S, '''Dinger ME''', Gardner PP, Poole AM, Ganley ARD. [https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe/evag042/8498184 Pervasive transcription in the human genome exceeds background noise.] ''Genome Biology and Evolution'' 25:evag042.
 #Holliday H, Khan A, Ehteda A, Nguyen H, Ross SE, Jayatilleke N, Gopalakrishnan A, Wang E, Sanguino YC, Kavanagh D, Guo X, Liu J, Lawrence D, Sun CX, Lehmann R, Ip CK, Lee A, Rangel-Sanchez L, Li W, Salomon R, Firestein R, Weatheritt RJ, Valdes-Mora F, '''Dinger ME''', Phoenix TN, Mayoh C, Rayner BS, Tsoli M, Ziegler DS (2026). [https://doi.org/10.1126/scitranslmed.adr1557 Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma.] ''Science Translational Medicine'' 18:eadr1557.

@@ Line 3: / Line 3: @@
 <table><tr><td>
-Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 171 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 74]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
+Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 172 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 74]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
 Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research]. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome. Prior to moving to Sydney, Marcel headed the Cancer Transcriptomics laboratory at the [http://www.di.uq.edu.au/ Diamantina Institute] at the [http://www.uq.edu.au/ University of Queensland]. Marcel undertook his postdoctoral studies at the [http://imb.uq.edu.au/ Institute for Molecular Bioscience] where he studied the role of long noncoding RNAs in mammalian development and disease. During his postdoc, Marcel led a number of key studies demonstrating the dynamic and specific expression of long noncoding RNAs that prompted extensive functional studies of these transcripts that were commonly assumed to be “junk”.

@@ Line 29: / Line 29: @@
 <nowiki>*</nowiki> '''Authors contributed equally'''
-Ross SE, Holliday H, Wang E, Zeraati M, Tsoli M, Ziegler DS, '''Dinger ME''' (2026). [https://www.nature.com/articles/s41419-026-08647-8 RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.] ''Cell Death and Disease'' Published online March 26. doi: 10.1038/s41419-026-08647-8.
+#Ross SE, Holliday H, Wang E, Zeraati M, Tsoli M, Ziegler DS, '''Dinger ME''' (2026). [https://www.nature.com/articles/s41419-026-08647-8 RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition.] ''Cell Death and Disease'' Published online March 26. doi: 10.1038/s41419-026-08647-8.
 #Adey BN, Maddock DJ, Hermann-Le Denmat S, '''Dinger ME''', Gardner PP, Poole AM, Ganley ARD. [https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe/evag042/8498184 Pervasive transcription in the human genome exceeds background noise.] ''Genome Biology and Evolution'' 25:evag042.
 #Holliday H, Khan A, Ehteda A, Nguyen H, Ross SE, Jayatilleke N, Gopalakrishnan A, Wang E, Sanguino YC, Kavanagh D, Guo X, Liu J, Lawrence D, Sun CX, Lehmann R, Ip CK, Lee A, Rangel-Sanchez L, Li W, Salomon R, Firestein R, Weatheritt RJ, Valdes-Mora F, '''Dinger ME''', Phoenix TN, Mayoh C, Rayner BS, Tsoli M, Ziegler DS (2026). [https://doi.org/10.1126/scitranslmed.adr1557 Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma.] ''Science Translational Medicine'' 18:eadr1557.

@@ Line 29: / Line 29: @@
 <nowiki>*</nowiki> '''Authors contributed equally'''
 #Adey BN, Maddock DJ, Hermann-Le Denmat S, '''Dinger ME''', Gardner PP, Poole AM, Ganley ARD. [https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe/evag042/8498184 Pervasive transcription in the human genome exceeds background noise.] ''Genome Biology and Evolution'' 25:evag042.
 #Holliday H, Khan A, Ehteda A, Nguyen H, Ross SE, Jayatilleke N, Gopalakrishnan A, Wang E, Sanguino YC, Kavanagh D, Guo X, Liu J, Lawrence D, Sun CX, Lehmann R, Ip CK, Lee A, Rangel-Sanchez L, Li W, Salomon R, Firestein R, Weatheritt RJ, Valdes-Mora F, '''Dinger ME''', Phoenix TN, Mayoh C, Rayner BS, Tsoli M, Ziegler DS (2026). [https://doi.org/10.1126/scitranslmed.adr1557 Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma.] ''Science Translational Medicine'' 18:eadr1557.

@@ Line 5: / Line 5: @@
 Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 170 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 74]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
-Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research]. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome.
+Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research]. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome. Prior to moving to Sydney, Marcel headed the Cancer Transcriptomics laboratory at the [http://www.di.uq.edu.au/ Diamantina Institute] at the [http://www.uq.edu.au/ University of Queensland]. Marcel undertook his postdoctoral studies at the [http://imb.uq.edu.au/ Institute for Molecular Bioscience] where he studied the role of long noncoding RNAs in mammalian development and disease. During his postdoc, Marcel led a number of key studies demonstrating the dynamic and specific expression of long noncoding RNAs that prompted extensive functional studies of these transcripts that were commonly assumed to be “junk”.
 Marcel has worked in informatics and genomics since 1998 in both commercial and academic capacities. As an entrepreneur in the early 2000s, Marcel established and grew three successful businesses; (i) a software company that produced DNA sequence analysis software, (ii) an information company that licensed databases to 10,000s of libraries and (iii) a web hosting company that became the fastest growing in New Zealand (exited by trade sale). He is the former President of the [https://agtagenomics.org.au Australasian Genomics Technologies Association (AGTA)], the principal body for the promotion of genomics research and technologies in Australasia. He has held board roles on [https://ncig.anu.edu.au National Centre for Indigenous Genomics (NCIG)], an [https://www.anu.edu.au ANU]-based centre focused on using genomics to improve the health and well-being of Australia's First Peoples, [http://genieus.co GenieUs], a genomics and machine-learning technology startup dedicated to finding new therapies for neurodegenerative diseases, and [http://www.scientiaclinicalresearch.com.au Scientia Clinical Research], a world-class clinical trials facility with a focus on early stage clinical research.

@@ Line 5: / Line 5: @@
 Marcel Dinger is Professor of Genome Biology and [https://www.sydney.edu.au/science/about/our-people.html Dean of Science] at the [https://www.sydney.edu.au University of Sydney]. He has 23 years' experience in genomics as both an academic and entrepreneur. He has published [https://www.webofscience.com/wos/author/record/2152005 170 papers] that have collectively been cited [https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en>37,000 times] ([https://scholar.google.com.au/citations?user=UFNwjvsAAAAJ&hl=en Google Scholar h-index 74]) and is (co)-founder of four startups in biotechnology and IT. He is a board director of [https://pryzm.health/ Pryzm Health], a digital health enterprise focused on optimising patient care by empowering physicians with AI-based clinical decision support technology.
-Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research] from 2012-2018. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome. He is the former President of the [https://agtagenomics.org.au Australasian Genomics Technologies Association (AGTA)], the principal body for the promotion of genomics research and technologies in Australasia. He has held board roles on [https://ncig.anu.edu.au National Centre for Indigenous Genomics (NCIG)], an [https://www.anu.edu.au ANU]-based centre focused on using genomics to improve the health and well-being of Australia's First Peoples, [http://genieus.co GenieUs], a genomics and machine-learning technology startup dedicated to finding new therapies for neurodegenerative diseases, and [http://www.scientiaclinicalresearch.com.au Scientia Clinical Research], a world-class clinical trials facility with a focus on early stage clinical research.
+Marcel served as Head of [https://www.unsw.edu.au/science/our-schools/babs School of Biotechnology and Biomolecular Sciences] at [https://www.unsw.edu.au UNSW Sydney] from 2019 to 2022. Prior to his role at UNSW, Marcel was the Founding Chief Executive Officer of Genome.One, one of the first companies in the world to provide clinical whole genome sequencing services, and inaugural Head of the [http://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/clinical-genomics Kinghorn Centre for Clinical Genomics] (KCCG) at the [https://garvan.org.au/ Garvan Institute of Medical Research]. As CEO of Genome.One, he brought together his expertise in informatics, biology and business to manage and direct a world-class clinical genomics service. As Head of KCCG, Marcel led a translational research laboratory that aimed to realise the utility of genomic medicine in routine clinical practice and explore the clinical value of non-protein-coding regions of the genome. He is the former President of the [https://agtagenomics.org.au Australasian Genomics Technologies Association (AGTA)], the principal body for the promotion of genomics research and technologies in Australasia. He has held board roles on [https://ncig.anu.edu.au National Centre for Indigenous Genomics (NCIG)], an [https://www.anu.edu.au ANU]-based centre focused on using genomics to improve the health and well-being of Australia's First Peoples, [http://genieus.co GenieUs], a genomics and machine-learning technology startup dedicated to finding new therapies for neurodegenerative diseases, and [http://www.scientiaclinicalresearch.com.au Scientia Clinical Research], a world-class clinical trials facility with a focus on early stage clinical research.
 In 2011, Marcel headed the Cancer Transcriptomics laboratory at the [http://www.di.uq.edu.au/ Diamantina Institute] at the [http://www.uq.edu.au/ University of Queensland]. Marcel undertook his postdoctoral studies at the [http://imb.uq.edu.au/ Institute for Molecular Bioscience] where he studied the role of long noncoding RNAs in mammalian development and disease. During his postdoc, Marcel led a number of key studies demonstrating the dynamic and specific expression of long noncoding RNAs that prompted extensive functional studies of these transcripts that were commonly assumed to be “junk”.